New Publication in Nature

New publication in Nature Communications

We are very pleased to announce that our latest research entitled “Critical slowing down as a biomarker for seizure susceptibility” has been published in the May issue of Nature communications. 

The research explores the way the human brain changes state, and how epilepsy can impact the severity of these stage changes; potentially causing loss of consciousness, injury and even death.

Using long-term intracranial electroencephalography (iEEG) recordings from fourteen patients with focal epilepsy, we monitored key signatures of critical slowing down prior to seizures.

Impactful insights into seizure forecasting

The metrics used to detect critical slowing down fluctuated over temporally long scales (hours to days). This is longer than would be detectable in standard clinical evaluation settings. 

Our results provide strong validation of theoretical models and demonstrate that critical slowing down is a reliable indicator of seizure activity that could be used in seizure forecasting algorithms.

Our results provide strong validation of theoretical models and demonstrate that critical slowing down is a reliable indicator of seizure activity that could be used in seizure forecasting algorithms.

Impactful insights into seizure forecasting

The metrics used to detect critical slowing down fluctuated over temporally long scales (hours to days). This is longer than would be detectable in standard clinical evaluation settings. 

Our results provide strong validation of theoretical models and demonstrate that critical slowing down is a reliable indicator of seizure activity that could be used in seizure forecasting algorithms.

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